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Study of nicotinic receptor SNPs relationship to cognition and neuropathology in aging

Currently utilising the ROS/MAP database to study relationships between polymorphisms in the a5 nicotinic subunit gene CHRNA5, and aging and Alzheimer's disease phenotypes.

We found a possible role of CHRNA5 in regulating amyloid processing and toxicity in a cell-type specific manner.

Power in Numbers

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